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Hallucinogens
Although hallucinogen use can lead to
hallucinogen abuse, it is believed that for most hallucinogenic
drugs, hallucinogen addiction is actually more a function of the
tolerance experienced when used on a frequent basis, than actual
dependence on the drug. In fact there is no evidence that LSD, the
most commonly known of all hallucinogens, produces any physical
withdrawal symptoms when chronic use is stopped. Even the tolerance
developed during frequent use appears to diminish rapidly, usually
within a few short days of abstinence. This is certainly not the
case with 'dissociative drugs', such as PCP, which are often taken
for their hallucinogenic effects.
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Hallucinogens produce profound distortions
in the user's perceptions. While under the influence of a hallucinogen,
reality is perceived contrary to common sense. Images are seen and
sounds heard that simply do not exist, at least within the parameters
of our normal sense of reality. Users often describe having seen sounds
and heard colors while under the influence. Some hallucinogenic drugs
can also produce rapid, intense emotional swings.
What are Hallucinogens?
Hallucinogens disrupt the interaction of nerve cells and
the neurotransmitter serotonin. Serotonin is distributed throughout
the brain and spinal cord, and is instrumental in the control of behavior,
perception, and the regulatory systems such as mood, hunger, body
temperature, sex drive, muscle control, and sensory perception.
As referenced to above, LSD is by far the drug most commonly identified
with the term "hallucinogen", and is also the most widely
used and abused drug of its type. When the average person thinks hallucinogen,
they think LSD or acid. The characteristics of LSD's action and its
effects are characteristic of the other hallucinogens, including mescaline,
psilocybin, and ibogaine.
What are Dissociative Drugs?
PCP
(phencyclidine) and ketamine are drugs originally developed as general
anesthetics for surgery, and are referred to as dissociative drugs.
Dissociative drugs distort perceptions of sight and sound and produce
feelings of detachment, called dissociation, from the environment
and from the self. However, these mind-altering effects are not hallucinations.
Therefore, PCP and ketamine are not hallucinogens, but rather more
properly known as "dissociative anesthetics."
Dextromethorphan,
which is a widely available cough suppressant, can produce effects
similar to those of PCP and ketamine when taken in high enough doses.
Dissociative drugs
act by altering the distribution of the neurotransmitter glutamate
throughout the brain, which is involved in the perception of pain,
responses to the environment, and memory. PCP is generally what people
associate with the term 'dissociative drugs' and the documentation
on the dangers of PCP are plentiful.
Developed in the 1950's as an intravenous anesthetic, PCP, commonly
known as angel dust, is sometimes sold to unsuspecting users as LSD,
mescaline, or other hallucinogens. PCP is typically taken by the oral
ingestion of tablets or capsules containing the powdered form, and
is commonly snorted or smoked in combination with marijuana or tobacco.
PCP, as well as having hallucinogenic characteristics, has the effects
of a stimulant, an anesthetic, or a narcotic pain-killer, depending
on how much is taken. Because of its unpredictable hallucinogenic
properties, PCP episodes can vary greatly. PCP users are commonly
brought to emergency rooms around America due to its rather bizarre
and unpleasant psychological effects or because of overdose. Continued
PCP use can lead to psychological dependence (addiction), as well
as tolerance.
Use of PCP in humans was discontinued in 1965, but is still used as
a veterinary tranquilizer and is also illegally manufactured in laboratories.
Why do people take Hallucinogens?
Hallucinogenic drugs have played an important role in the evolution
of human history. For literally thousands of years, cultures in different
parts of the world have ingested plants with hallucinogenic properties
in order to induce altered states of consciousness, states of detachment
from reality, and to precipitate "visions" thought to provide
mystical insight.
The hallucinogenic effects of these plants are cause by the chemical
compounds contained within them, such as mescaline, psilocybin, and
ibogaine. The compounds are molecularly similar to serotonin, and
produce their effects by disrupting normal functioning of the serotonin
system. Throughout history, hallucinogenic plants have been used extensively
for social and religious rituals.
Availability of these hallucinogenic plants has always been limited
by climate and soil conditions, and thus has not been readily available
to all cultures. However, after the development of LSD, hallucinogens
could be manufactured petty much anywhere. This phenomenon of modern
society, called global availability, has resulted in wide spread hallucinogen
abuse. Hallucinogen abuse became more widespread gradually, and then
in the 1960s it increased dramatically. All LSD manufactured in this
country is intended for illegal use since LSD has no accepted medical
use in the United States. Fortunately, hallucinogen abuse does not
lead to hallucinogen addiction (dependency), however, the same can
not be said about 'dissociative drugs', such as PCP, which are often
taken mistakenly as a hallucinogens and which are much more dangerous.
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